Natural Armor. Your body is particularly tough and resilient to damage. This may be in the form of tough, scaly skin, or perhaps a partial exoskeleton. When you aren’t wearing armor, your AC is 13 + your Dexterity modifier. You can use your natural armor to determine your AC if the armor you wear would leave you with a lower AC. A shield’s benefits apply as normal while you use your natural armor. This mutation costs 3 points.

Natural Weapon. You have a natural weapon that you are proficient in. This could be a bite, claw, quill, club tail, tentacle or other feature. You can choose to add your strength or dexterity modifier to the attack roll and deal 1d6 + strength or dexterity modifier damage. The damage type should be selected when you take this trait; bludgeoning, piercing, poison, or slashing damage. At your GM's discretion, this anatomical feature may be able to hold items, but is not dexterous to use anything it holds. This mutation costs 2 points.

You can take this mutation an additional 2 times, spending 1 point each time. The first time, the damage of your natural weapon increases to 1d8. The second time, the damage of your natural weapon increases to 1d10.

Photosynthesis. Rather than eating, you can sustain yourself on sunlight. By spending at least 2 hours in direct sunlight, you are treated as having eaten enough food for that day. At your GM's discretion, you may use other powerful sources of ultraviolet light to gain this benefit instead of sunlight, such as a tanning bed. This mutation costs 1 point.

Poison Breath. You can use your action to exhale a cloud of poison. When you do so, each creature in a 15 ft. cone originating from you must make a constitution saving throw. The DC for this saving throw equals 8 + your Constitution modifier + your proficiency bonus. A creature takes 2d6 poison damage on a failed save, and half as much damage on a successful save. The damage increases to 3d6 at 6th level, 4d6 at 11th level, and 5d6 at 16th level.

After you use your poison breath, you can’t use it again until you complete a short or long rest. This mutation costs 6 points.

Quadruped Dash. You are able to move swiftly on all fours. While you are prone you can run on all fours if your hands are free. While doing so, your walking speed increases by 10 feet. Additionally, you do not have disadvantage on melee attack rolls while you are prone. This mutation costs 2 points.

Resilient Mind. You have advantage on saving throws against being charmed, and magic can’t put you to sleep. This mutation costs 2 points. You can take this mutation one additional time, spending 2 points to gain resistance to psychic damage.

Slippery. You have advantage on ability checks and saving throws made to escape a grapple. This mutation costs 3 points.

Deafness. You are perpetually affected by the Deafened condition. This mutation gains you 2 mutation points.

Flesh Hunger. You no longer need to eat, in the traditional sense. Normal food no longer contributes to the food you must eat to avoid exhaustion each day, though you may still eat normal food if you wish. Instead, you must eat fresh, raw meat, that has been dead for a couple of days at most. See the Player's Handbook for rules on eating and drinking. This mutation gains you 4 mutation points

Wretched Appearance. You suffer disadvantage on all Charisma ability checks against creatures that can see you. A proper disguise thwarts the disadvantage until discovered. This mutation gains you 3 mutation points.

Monacular Vision. You were born with only one eye. You have disadvantage on Wisdom (perception) checks that rely on sight to see anything further than 30 feet from you, and you have disadvantage on ranged attack rolls against creatures further than 30 feet from you. This mutation gains you 2 mutation points.

Sensitive Ears. You have vulnerability to thunder damage. This mutation gains you 8 mutation points.

Slowness. Your base walking speed is reduced by 5 feet. This mutation gains you 2 mutation points. You can take this mutation one additional time, gaining 2 points to reduce your speed by a further 5 feet.

Sunlight Sensitivity. You have disadvantage on attack rolls and on Wisdom (Perception) checks that rely on sight when you, the target of your attack, or whatever you are trying to perceive is in direct sunlight. This mutation gains you 3 mutation points.

Unnatural Allergy. You have a horrible reaction to a particular substance or energy, causing you harm when you are in contact with it. Work with your GM as to what this substance or energy is; the substance or energy you choose should be common enough that you could reasonably encounter it. Some common options include sunlight, silver, or gold. When you come into direct contact with the substance or energy, you take 1d4 necrotic damage. This damage ignores any damage immunities and resistances you have. You also take this damage if you start your turn in direct contact with the substance or energy. Additionally, when in contact with the substance, you suffer extreme pain and have disadvantage on attack rolls and ability checks. This mutation gains you 4 mutation points.

Credits

Document and contents by Dylan Richards (Reddit: u/Altavus , Tumblr: decision-paralysis, Blogger: Decision Paralysis)